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Substituted 1,2,3 triazole angiotensin II antagonists
Filed: July 10th, 1991 [Granted]
Assignee: E I Du Pont de Nemours and Company
Patent Number: 5189048
170 CH2OCH3 n-butyl CO2H H Single bond 129-134 171 n-butyl CH2OCH3 C02H H Single bond 112-119 172 (CH2)2CH=CH2 CH2OCH3 C02H H Single bond 100-106 173 ...
Substituted pyrrole angiotensin II antagonists
Filed: March 26th, 1990 [Granted]
Assignee: E I Du Pont de Nemours and Company
Patent Number: 5043349
176 n-propyl CH2OH CO2H H Single bond 119-125 177 CH2OH n-propyl CO2H H Single bond 51-58 178 n-propyl CHO C02H H Single bond (amorph) 179 CHO n-propyl C02H ...
Treatment of hypertension with 1,2,4-angiotensin II antagonists
Filed: December 6th, 1988 [Granted]
Assignee: E I Du Pont de Nemours and Company
Patent Number: 5015651
Rl R2 R3 R5 A 314 n-propyl O || CH=CHCOH3 315 CH=CHCH3 CH2COPh C02H H Single bond 316 CH=CHCH3 CH2COCH2Ph C02H H Single bond 317 CH=CHCH3 CH2CO(CH2)2Ph C02H ...
Substituted pyrazole angiotensin II antagonists
Filed: August 5th, 1992 [Granted]
Assignee: E I Du Pont de Nemours and Company
Patent Number: 5315013
R' R2 R3 R5 A 113 n-propyl O || C02H H Single bond CH2SCH3 o 114 n-propyl CH= CHCH2OH C02H H Single bond 115 n-propyl CH=CHCH2OCH3 C02H H Single bond 116 ...
Substituted 1,2,4-triazole angiotensin II antagonists
Filed: March 8th, 1991 [Granted]
Assignee: E I Du Pont de Nemours and Company
Patent Number: 5093346
Rl R2 R3 R5 A mp (°C.) 235 n-propyl CH2SO2CH3 C02H H Single bond 236 n-propyl CH =CHCH2OH C02H H Single bond 237 n-propyl CH=CHCH2OCH3 C02H H Single bond 238 ...
Renal-selective biphenylalkyl 1H-substituted-1,2,4-triazole angiotensin II ...
Filed: August 28th, 1990 [Granted]
Assignee: G D Searle Co
Patent Number: 5217985
... single Ex:# Rs ABEP 85 C02H single bond HH COCH3 86 C02H single bond HH COCH2CI 87 C02H single bond HH COC4H9 88 C02H single bond H CH3 COCH3 89 C02H ...
Renal-selective biphenylmethyl imidazole angiotensin II antagonists for ...
Filed: December 19th, 1991 [Granted]
Assignee: G D Searle Co
Patent Number: 5302610
... Rl R2 ABEP 202 CI X C02H single bond H C2H5 COCH3 203 CI X CN4H C3H6(n) HH COCH3 204 CI X CN4H single bond HH COCH2Cl 205 CI X CN4H single bond HH ...
Treatment of CNS disorders with 4,5,6,7-tetrahydro-1H-imidazo (4,5 ...
Filed: September 20th, 1990 [Granted]
Assignee: E I du Pont de Nemours and Company
Patent Number: 5091390
... Where R!=H, R6=3— CH3, , R3=COCH(Ph)2, alkyl =CH3 A) A solution of 2.03 g of ... 3-CH2C6H5 9 C3H7 C02H CH2-2-thicnyl single bond CO2H 3-CH3 10 C4H9 ...
