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Substituted benzene derivatives useful as neuraminidase inhibitors
Filed: March 30th, 1995 [Granted]
Assignee: BioCryst Pharmaceuticals Inc
Patent Number: 5602277
... CH2OH, — NHC(=NH)NH2, — NHC(=NCN)NH2, — CH=CHCH2OH, —NHCN, and CH=NOH; m is 0-2; with the following provisos: 65 (1) when R1 is C02H and R4 is (CH2).
Substituted pyrazole angiotensin II antagonists
Filed: August 5th, 1992 [Granted]
Assignee: E I Du Pont de Nemours and Company
Patent Number: 5315013
... C02H H Single bond 230 n-propyl CON Nn-Bu C02H H Single bond CH=CHCH2OCH ... 235 n-propyl CH2SO2CH3 C02H H Single bond 236 n-propyl CH=CHCH2OH C02H H ...
Substituted 1,2,3-triazole angiotensin II antagonists
Filed: March 26th, 1990 [Granted]
Assignee: E I du Pont de Nemours and Company
Patent Number: 5081127
R1 R2 R3 R5 A 307 n-propyl CON Nn-Bu C02H H Single bond 308 n-propyl r~\ C02H H Single bond CON N— Ph 309 n-propyl CH=CHCH2OH C02H H Single bond 310 ...
Substituted 1,2,4-triazole angiotensin II antagonists
Filed: March 8th, 1991 [Granted]
Assignee: E I Du Pont de Nemours and Company
Patent Number: 5093346
R1 R2 R3 R5 A 307 n-propyl / \ C02H H Single bond 308 n-propyl CON Nn-Bu C02H H Single bond CON N— Ph \ / 309 n-propyl CH=CHCH2OH C02H H Single bond 310 ...
Substituted pyrrole angiotensin II antagonists
Filed: March 26th, 1990 [Granted]
Assignee: E I Du Pont de Nemours and Company
Patent Number: 5043349
55 56 TABLE 2-continued 1,2,4-TRIAZOLES N — NN R3 R5 A C02H H Single C02H ... 113 n-propyl O || C02H H Single bond CH2SCH3 O 114 n-propyl CH=CHCH2OH C02H H ...
Treatment of hypertension with 1,2,4-angiotensin II antagonists
Filed: December 6th, 1988 [Granted]
Assignee: E I Du Pont de Nemours and Company
Patent Number: 5015651
65 66 TABLE 3-continued PYRAZOLES R2 NR? R3 ^ C02H N— Ph mp CO ... CH2SCH3 235 n -propyl CH2SO2CH3 C02H H Single bond 236 n-propyl CH=CHCH2OH C02H H Single ...
Substituted vinyl cephalosporins
Filed: December 28th, 1983 [Granted]
Assignee: Bristol-Myers Company
Patent Number: 4520022
CHCONH- V 1 '}— N J— CH= C02H CH2 45 50 IV H3-i HO— (' V— CHCONH NH2 OS VII V 1 N ^5^— CH=CHCH2OH C02H US Pat. No. 4094978 Col.
Imidazolylthioalkenoic acids and -alkenols and leukotriene antagonistic ...
Filed: October 24th, 1986 [Granted]
Assignee: Smithkline Beckman Corporation
Patent Number: 4769386
... CH CHCH2OH ^C=C RSH >(VIH) / \ HH 25 (11) Compound (8) wherein THP is a ... 5.3 CH3 — C02H H 6.8 CH3 — C02H CH3 6.9 <a>CH3 — C02H CH3 6.9 (fl>CH3 — C02H ...
