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Substituted benzene derivatives useful as neuraminidase inhibitors
Filed: March 30th, 1995 [Granted]
Assignee: BioCryst Pharmaceuticals Inc
Patent Number: 5602277
57 58 R3 is selected from the group consisting of — H, — OR, ... CH2OH, — NHC(= NH)NH2, — NHC(=NCN)NH2, — CH=CHCH2OH, —NHCN, and CH=NOH; m is 0-2; ...
Substituted 1,2,3 triazole angiotensin II antagonists
Filed: July 10th, 1991 [Granted]
Assignee: E I Du Pont de Nemours and Company
Patent Number: 5189048
307 n-propyl / \ C02H H Single bond CON Nn-Bu 308 n-propyl / \ C02H H Single bond CON N— Ph 309 n-propyl CH=CHCH2OH C02H H Single bond 310 n-propyl ...
Substituted 1,2,4-triazole angiotensin II antagonists
Filed: March 8th, 1991 [Granted]
Assignee: E I Du Pont de Nemours and Company
Patent Number: 5093346
R1 R2 R3 R5 A 307 n-propyl / \ C02H H Single bond 308 n-propyl CON Nn-Bu C02H H Single bond CON N— Ph \ / 309 n-propyl CH=CHCH2OH C02H H Single bond 310 ...
Substituted pyrazole angiotensin II antagonists
Filed: August 5th, 1992 [Granted]
Assignee: E I Du Pont de Nemours and Company
Patent Number: 5315013
225 n-propyl 226 n-propyl CON 0 I — \ CON NH CO2H H Single bond CO2H H Single ... 235 n-propyl CH2SO2CH3 C02H H Single bond 236 n-propyl CH=CHCH2OH C02H H ...
Substituted pyrrole angiotensin II antagonists
Filed: March 26th, 1990 [Granted]
Assignee: E I Du Pont de Nemours and Company
Patent Number: 5043349
55 56 TABLE 2-continued 1,2,4-TRIAZOLES N — NN R3 R5 A C02H H Single C02H ... O 114 n-propyl CH=CHCH2OH C02H H Single bond 115 n-propyl CH=CHCH2OCH3 C02H H ...
Treatment of hypertension with 1,2,4-angiotensin II antagonists
Filed: December 6th, 1988 [Granted]
Assignee: E I Du Pont de Nemours and Company
Patent Number: 5015651
65 66 TABLE 3-continued PYRAZOLES R2 NR? R3 ^ C02H N— Ph mp CO ... CH2SCH3 235 n -propyl CH2SO2CH3 C02H H Single bond 236 n-propyl CH=CHCH2OH C02H H Single ...
Imidazolylthioalkenoic acids and -alkenols and leukotriene antagonistic ...
Filed: October 24th, 1986 [Granted]
Assignee: Smithkline Beckman Corporation
Patent Number: 4769386
... CH CHCH2OH ^C=C RSH >(VIH) / \ HH 25 (11) Compound (8) wherein THP is a ... Kg CH3 HH 5.9 CH3 H -CH2C02H 6.1 CH3CHj HH 5.3 CH2=CHCH2 HH 5.3 CH3 — C02H H ...
Angiotensin II receptor blocking imidazoles
Filed: December 6th, 1988 [Granted]
Assignee: E I Du Pont de Nemours and Company
Patent Number: 5138069
... 1 n-propyl H CH2OH NOCH3 4—0 CF3S02N H 4— C CF3S02N H C02H 313 1 n-pentyl CI CH2OH C02H .314 1 n-butyl CI CH=CHCH2OH 314A 1 n-butyl CF3 C02CH2OOCC(CH3)3 ...
