United Slates Patent im Cronin et al. [in 3872171 [45] Mar. 18, 1975 [54] POLY AMINES AS ANTIVIRAL AGENTS IN ANIMALS [75] Inventors: Timothy H. Cronin, ...

US005258039A United States Patent [19] [ii] Patent Number: 5258039 Goh et al. ... STORING COMPOSITE PROSTHETIC FOOT [75] Inventors: James CH Goh; SL Toh; ...

... (CH2)2— CI O— CH2— S— CH3 O— CH2— Ph O— Ph O— CH2— CH=CH2 O— CH2— C=CH O— CH2— O— C2H5 H OH O— CH3 O— C2H5 O-11-C3H7 Oi-CjHy O-11-C4H9 O-1-C4H9 OS-C4H9 ...

... for example C4-C6alkylene interrupted by oxygen or sulfur. An especially preferred meaning of R2 is — CH2CH2 — O — CH,CH, — O — CH,CH, — or — CH,CH, ...

15 16 TABLE A-2-continued Rl R1 (1) (CH3) O—R-fi—N/ XO Yn (CH3)m 58 C1 1 C1 0 CH (CH3) H 3'-CH3 132—l33.5 59 Cl l Cl 0 CI-l(CH3) H 3'-CF; 1ZS—126 61 Cl 1 Cl ...

00 (m, 2H, :CH+CHH), 5.49 (s, 1H, CHH), 5.31-5.34 (m, 1H, CHO), 3.17 (br s, 1H, CH), 2.85 (br s, 1H, CH), 2.13-2.19 (m, 1H, CHH), 1.88 (s, 3H, CH3), ...

-continued o Vv - CH2CH=CH(CH2)3COOR3 (T) deprotection ... (T) deprotection (2) optional esterification and/or salification CH2CH=CH(CH2)3COOR1 ...

OCH3 ON —( Compound 35 ( >< N =< CCH2C1 _ CH— N ^ \ OCH3 N The above UK ... c2H5 o / \VN cch2ci 25 \ ^ CH— CH2— OCH3 CH3 CH3 Investigations of the present ...